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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TACC3
All Species:
6.67
Human Site:
S497
Identified Species:
16.3
UniProt:
Q9Y6A5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6A5
NP_006333.1
838
90360
S497
A
L
N
S
A
S
T
S
L
P
T
S
C
P
G
Chimpanzee
Pan troglodytes
XP_001158492
1012
110340
M625
T
N
Q
K
W
T
C
M
T
V
D
L
E
S
D
Rhesus Macaque
Macaca mulatta
XP_001101192
833
90010
S476
A
L
N
S
A
S
I
S
L
P
T
S
C
P
G
Dog
Lupus familis
XP_536226
945
101827
R604
G
E
E
G
A
A
E
R
A
G
A
S
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ11
631
70608
E331
G
A
E
V
D
Y
L
E
Q
F
G
T
S
S
F
Rat
Rattus norvegicus
NP_001004424
585
65028
V285
V
L
G
A
G
A
E
V
D
Y
L
E
Q
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001004429
890
99494
S513
S
A
D
S
G
K
R
S
M
P
A
E
E
I
K
Frog
Xenopus laevis
Q9PTG8
931
102522
E565
S
S
D
M
T
P
P
E
I
N
G
T
D
S
E
Zebra Danio
Brachydanio rerio
NP_997746
942
103747
A579
V
P
E
P
D
F
M
A
V
P
E
S
I
A
D
Tiger Blowfish
Takifugu rubipres
NP_001011729
878
96473
T523
Q
A
E
Q
L
P
E
T
T
L
Q
T
L
S
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.3
84.1
42.6
N.A.
45.9
47.3
N.A.
N.A.
38.7
36.8
32.2
32.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
44.5
88.3
53.7
N.A.
57.4
56.2
N.A.
N.A.
52.2
52
50.1
49.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
20
N.A.
0
13.3
N.A.
N.A.
20
0
13.3
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
93.3
26.6
N.A.
6.6
26.6
N.A.
N.A.
40
26.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
30
0
10
30
20
0
10
10
0
20
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
20
0
0
% C
% Asp:
0
0
20
0
20
0
0
0
10
0
10
0
10
0
30
% D
% Glu:
0
10
40
0
0
0
30
20
0
0
10
20
20
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
10
% F
% Gly:
20
0
10
10
20
0
0
0
0
10
20
0
0
0
30
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
10
0
0
0
10
10
0
% I
% Lys:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
30
0
0
10
0
10
0
20
10
10
10
10
0
0
% L
% Met:
0
0
0
10
0
0
10
10
10
0
0
0
0
0
0
% M
% Asn:
0
10
20
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
10
0
10
0
20
10
0
0
40
0
0
0
30
0
% P
% Gln:
10
0
10
10
0
0
0
0
10
0
10
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
20
10
0
30
0
20
0
30
0
0
0
40
10
40
0
% S
% Thr:
10
0
0
0
10
10
10
10
20
0
20
30
0
0
0
% T
% Val:
20
0
0
10
0
0
0
10
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _